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. 2011 Aug 16;2(6):1225–1231. doi: 10.3892/ol.2011.382

Table I.

Parameters used in the various systems for the histological grading of malignancy.

Authors Year Parameters Refs.
Wahi 1971 Keratinization of individual cells, formation of horn pearls, presence of intercellular bridges, number and aspect of mitosis figures, degree of cell and nuclear pleomorphism and presence of multi-nucleated giant cells. (4)
Jakobsson et al 1973 Neoplastic structure, keratinization, nuclear pleomorphism, number of mitoses, mode and stage of invasion, vascular invasion and lymphoplasmocyte inflammatory infiltrate. (5)
Crissman, Gluckman, Cummings 1984 Degree of keratinization, nuclear pleomorphism, number of mitoses, invasion pattern, inflammatory infiltrate and vascular invasion. (6)
Anneroth, Batsakis, Luna 1987 Degree of keratinization, cell pleomorphism, number of mitoses, invasion pattern, stage of invasion and lymphoplasmocyte inflammatory infiltrate. (7)