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. 2011 Aug 16;2(6):1225–1231. doi: 10.3892/ol.2011.382

Table VI.

Correlation between inflammatory infiltrate intensity and positivity for CD8 and FOXP3 expression.

Inflammatory infiltrate intensity

Dysplasia (n=20) Carcinoma (n=40)


Markers Mild Mod. no. (%) Int. Total r P-value Mild Mod. no. (%) Int. Total r P-value
CD8
 <5% 2(40) 1 (10) 1 (20) 4 (20) 11 (100) 6 (60) 10 (50) 27 (67.5)
 5–50% 2 (40) 2 (20) 0 (0) 4 (20) 0.391 N.S. 0 (0) 1 (10) 2 (10) 3 (7.5) 0.365 <0.05a
 >50% 1 (20) 7 (70) 4 (80) 12 (60) 0 (0) 2 (20) 8 (40) 10 (25.0)
FOXP3
 <5% 3 (60) 6 (60) 2 (40) 11 (55) 7 (63.6) 6 (60) 11 (57.9) 24 (60.0)
 5–50% 1 (20) 2 (20) 2 (40) 5 (25) 0.109 N.S. 2 (18.2) 3 (30) 6 (31.6) 11 (27.5) 0.018 N.S.
 >50% 1 (20) 2 (20) 1 (20) 4 (20) 2 (18.2) 1 (10) 2 (10.5) 5 (12.5)

Spearman rank correlation coefficient.

a

P<0.05, statistically significant. NS, not significant.