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VEGF expression in high- and low-grade gliomas (magnification, ×400). (A) High-grade glioma showing numerous tumor cells with darkly-stained nuclei and a different shape. Brown-stained particles are shown in the cytoplasm and intercellular space. (B) Low-grade glioma with few VEGF-positive tumor cells. Arrow indicates a positive cell; brown particles are shown in the cytoplasm (magnification, ×400).
