Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Jul 5;3(7):e342. doi: 10.1038/cddis.2012.83

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2012 Macmillan Publishers Limited

This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

PMC Copyright notice

ADI-PEG20-induced autophagy and its modulation by chloroquine in lymphoma cells. (a) Malignant lymphoid cells were treated with ADI-PEG20 (500 ng/ml) either alone or in combination with chloroquine (CQ, 25 μM) and assessed for LC3-I and LC3-II levels by western blotting. (b) Follicular (Karpas-422) and CTCL (MyLa) lymphoma cells were treated with ADI-PEG20 and CQ for 72 h, and analysed for the subG1 fraction corresponding to apoptotic cells by flow cytometry; *P<0.001. (c) Similarly, primary malignant B lymphoma and CTCL (Sezary syndrome) lymphoma cells were studied using the ViaLight assay. Doxorubicin was used as a positive control for lymphoma cell cytotoxicity. *P<0.05, **P<0.001. Error bars represent S.D.