Fig. 4.

HSCF reverses the prolongation of blood coagulation produced by heparin in TEG assay. (A) A normal TEG scheme showing the R, Ang and MA parameters. R, the time a detectable clot is formed; Ang, the rate of clot formation; MA, clot strength. (B) TEG of non-koalin-activated coagulation of plasma in the absence or the presence of heparin without/with HSCF. (C) TEG of koalin-activated plasma coagulation in the absence or the presence of heparin without/with HSCF. (D) Summary of the parameters measured in (B) and (C). The data are presented as the mean ± SEM, n = 3. The significance of the difference between heparin and heparin + HSCF groups was analyzed by paired Student's t-test. #P < 0.001 (non-koalin-activated samples) and *P < 0.05 (koalin-activated samples).