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. Author manuscript; available in PMC: 2013 Jul 28.
Published in final edited form as: Cancer Lett. 2012 Mar 2;320(2):180–188. doi: 10.1016/j.canlet.2012.02.031

Figure 3. The number and max size of copy number alterations increases with UC progression.

Figure 3

A & C, The number of regions of copy number gain (A) and loss (C) increase with UC disease progression. Shown is the average number of regions of copy gain +/− SEM for non-UC, UC non-progressors, UC progressors at sites negative for dysplasia (located > 10 cm or < 10 cm from a site of dysplasia) and UC progressors at dysplastic sites. Asterisks indicate significant difference for comparisons to UC NP using Mann Whitney * p<0.05; ** p-value <0.01. B & D, The maximum size of regions of copy number gain (B) or loss (D) increase with UC disease progression. Shown is the maximum size (Mb) of regions of copy gain +/− SEM for non-UC, UC non-progressors, UC progressors at sites negative for dysplasia (located > 10 cm or < 10 cm from a site of dysplasia) and UC progressors at dysplastic sites. Asterisks indicate significant difference for comparisons to UC NP using Mann Whitney * p<0.05; ** p-value <0.01.