Table 3.
Characteristic/Diagnosis | Age, y | P Valuea | |||||
---|---|---|---|---|---|---|---|
| |||||||
Men | <35 (n = 234) | 35-44 (n = 142) | 45-54 (n = 166) | 55-64 (n = 89) | ≥65 (n = 138) | NA | |
Systolic blood pressure, mean (SD), mm Hg | 121.1 (11.9) | 122.3 (13.2) | 128.5 (17.3) | 136.1 (21.0) | 138.4 (21.5) | <.001 | |
Diastolic blood pressure, mean (SD), mm Hg | 69.2 (10.2) | 72.1 (11.1) | 77.7 (12.3) | 78.3 (11.2) | 75.5 (12.0) | <.001 | |
Body mass index, kg/m2 | 25.4 | 27.2 | 26.6 | 26.6 | 25.8 | .05 | |
Waist circumference, in | 33.3 | 36.0 | 35.7 | 36.4 | 36.3 | <.001 | |
Total cholesterol, mean (SD), mg/dL | 171 (41) | 194 (52) | 193 (45) | 195 (40) | 185 (37) | <.001 | |
LDL cholesterol, mean (SD), mg/dL | 113 (38) | 126 (48) | 130 (41) | 131 (38) | 119 (35) | <.009 | |
HDL cholesterol, mean (SD), mg/dL | 43 (14) | 47 (18) | 48 (18) | 45 (13) | 49 (16) | <.004 | |
Triglycerides, median (IQR), mg/dL | 70 (50) | 88 (72) | 86 (63) | 91 (62) | 77 (42) | .08 | |
Glucose, median (IQR), mg/dL | 83 (11) | 86 (16) | 90 (18) | 92 (19) | 93 (17) | <.001 | |
Hypertension, %b | 14 | 21 | 38 | 51 | 60 | <.001 | |
Diabetes, % | 1 | 4 | 12 | 16 | 20 | <.001 | |
Heart disease, % | 1 | 1 | 2 | 4 | 12 | <.001 | |
| |||||||
Women | n = 339 | n = 209 | n = 187 | n = 148 | n = 267 | ||
| |||||||
Systolic blood pressure mean (SD), mm Hg | 107.2 (1.3) | 117.0 (17.1) | 127.9 (19.8) | 135.5 (24.0) | 147.6 (24.0) | <.001 | |
Diastolic blood pressure, mean (SD), mm Hg | 66.8 (9.8) | 74.1 (11.9) | 80.1 (13.5) | 78.2 (13.1) | 77.2 (12.1) | <.001 | |
Body mass index, kg/m2 | 27.7 | 29.9 | 30.7 | 29.8 | 28.9 | <.001 | |
Waist circumference, in | 34.3 | 36.5 | 36.8 | 37.7 | 37.3 | <.001 | |
Total cholesterol, mean (SD), mg/dL | 165 (34) | 178 (34) | 188 (36) | 213 (40) | 203 (43) | <.001 | |
LDL cholesterol, mean (SD), mg/dL | 105 (32) | 114 (33) | 120 (34) | 139 (41) | 105 (32) | <.001 | |
HDL cholesterol, mean (SD), mg/dL | 46 (11) | 45 (13) | 48 (15) | 49 (14) | 50 (14) | <.001 | |
Triglycerides, median (IQR), mg/dL | 70 (44) | 90 (66) | 98 (64) | 100 (58) | 92 (65) | <.001 | |
Glucose, median (IQR), mg/dL | 80 (11) | 84 (14) | 88 (20) | 94 (23) | 96 (27) | <.001 | |
Hypertensionb, % | 11 | 26 | 48 | 62 | 81 | <.001 | |
Diabetesc, % | 3 | 11 | 15 | 30 | 37 | <.001 | |
Heart disease, % | 2 | 2 | 4.1 | 11 | 18 | <.001 |
Abbreviations: NA, not applicable; SD, standard deviation; LDL, low density lipoprotein; HDL, high density lipoprotein; IQR, interquartile range.
P values for trend for variables calculated using the Spearman correlation coefficient. P values for trend for categorical variables calculated using the Cochran-Armitage trend test.
A diagnosis of hypertension was based on participant self-report of hypertension or a blood pressure of 140/90 mm Hg or higher.
A diagnosis of diabetes was based on participant self-report or fasting glucose of 140 mg/dL.