Fig. 1.

A phylogenetic tree of identified and putative aaNATs from mosquitoes and other insects. Sequences were aligned using ClustalW, and the dendrogram was generated using the neighbor-joining method. Numbers at nodes show bootstrap values based on 1,000 replicates. The National Center for Biotechnology Information gi number is provided for each protein sequence. The three proteins for which crystal structures were solved in this report are shown with a gray background. Aea, Aedes aegypti; Ag, Anopheles gambiae; Bm, Bombyx mori; Cq, Culex quinquefasciatus; Dm, Drosophila melanogaster; Pa, Periplaneta americana.