Table 1.

Characteristics of studies included in the met-analyses

Study	Country	Study Design	Population Type	Analyzed		Mean Age (years)*		% Males		Dosage/day		Seizures assessed at
				PHY	LEV	PHY	LEV	PHY	LEV	PHY	LEV
Jones et al.[7]	USA	Obs	Severe TBI	41	32	34.6	33.2	75	73	N/A	1000 mg	7 Days
Milligan et al.[12]	USA	Obs	Supra-tentorial surgery	210	105	60	56.3	47	39	200-800 mg	500-3000 mg	7 Days & 30 Days
Lim et al.[13]	USA	RCT	Glioma (Post Operative)	8	15	48.2	42	100	60	300-400 mg	1000-3000 mg	6 months
Szaflarski[8]	USA	RCT	TBI, SAH	18	34	42	45	72.2	76.5	5 mg/kg	2000-3000 mg	3 Days & 6 months
Taylor et al.[14]	USA	Obs	ICH	25	60	70.2	63.3	52	40	NA	500-2000 mg	Till discharge
Murphy-Human et al.[15]	USA	Obs	SAH	297	145	57	55	30	28	NA	1000 mg	3 Days & Till discharge

Obs Observational study, RCT Randomized Controlled Trial, LEV Levetiracetam, PHY Phenytoin, TBI Traumatic brain injury, ICH Intracranial hemorrhage, SAH Subarachnoid hemorrhage.

* Mean age has been estimated wherever not directly available.