Table 3.
Risk of glioma and estimated cumulative pesticide exposure by type and target among participants with or without estimated exposures in the Upper Midwest Health Study
| Pesticide | Including proxy respondents | Excluding proxy respondents | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Type and Target |
Cases (n = 798) |
Controls (n = 1,175) |
|
Cases (n = 438) |
Controls (n = 1,141) |
|
||||
| na |
Exposureb |
n |
Exposure |
ORc (95 % CI) |
n |
Exposure |
n |
Exposure |
OR (95 % CI) |
|
| Insecticide |
128 |
177 (355) |
261 |
155 (263) |
0.99 (0.96, 1.02) |
73 |
139 (265) |
255 |
156 (265) |
0.99 (0.94, 1.04) |
| Animal |
89 |
117 (211) |
175 |
118 (179) |
0.97 (0.91, 1.03) |
48 |
106 (156) |
171 |
119 (181) |
0.98 (0.90, 1.07) |
| Crops |
78 |
156 (329) |
145 |
135 (228) |
1.00 (0.95, 1.04) |
42 |
120 (290) |
140 |
137 (232) |
0.99 (0.92, 1.06) |
| Buildings/Lots |
65 |
1.96 (5.39) |
130 |
1.99 (5.42) |
0.99 (0.96, 1.02) |
32 |
1.05 (1.75) |
125 |
2.05 (5.52) |
0.95 (0.88, 1.04) |
| Herbicide |
89 |
149 (255) |
163 |
212 (344) |
0.96 (0.91, 1.00) |
53 |
110 (198) |
160 |
214 (347) |
0.94 (0.88, 1.01) |
| Fungicide | 17 | 69.0 (89.5) | 32 | 97.5 (164) | 0.90 (0.72, 1.13) | 12 | 76.3 (92.1) | 32 | 97.5 (164) | 0.98 (0.78, 1.23) |
aNumber of participants with exposure estimated by an industrial hygienist. All other study participants are assigned zero exposure.
bMean (and standard deviation) of lifetime cumulative exposure in gram-years (g-years) for participants with estimated exposure. Cumulative exposure is calculated as 1,000 times the product of intensity (mg/hr) by decade, number of hours per day (hr/day), number of days per year (days/yr), and years by decade, and then summed across all decades.
cOdds ratio (and 95 % confidence intervals) of lifetime cumulative exposure (per 0.5 g for buildings/lots or per 50 g for all others based on median exposure), adjusted for matching variables (10-year age group, sex) and for age, and education.