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. 2012 May 29;7:12. doi: 10.1186/1750-9378-7-12

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Copyright ©2012 Hernandez-Montes et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License(http://creativecommons.org/licenses/by/2.0),which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Cytokines production after stimulation of antigenic receptor of PBL from patients with LSIL (LSIL) and normal donors without HPV (Normal). PBL from LSIL patients and normal donors were stimulated in culture with CD3/CD28 activating beads. After 5 days in culture, the concentration of: A) Th2 (IL-4, IL-5, IL-10) and B) Th1 (IL-2, TNFα, IFNγ) cytokines in supernatants were assayed by mean of a Cytometric Bead Array. A statistically significant difference was found for IL-2 production (* p < 0.05).