Table 2.
Mean (SD) unadjusted serum levels of markers of the vitamin D endocrine system and bone turnover at baseline and follow-up according to type of supplement
| Variable | n | Mean (SD) serum level at baseline | Mean (SD) serum level at follow-up | Mean (SD) change during intervention | p value(2) |
|---|---|---|---|---|---|
|
s-25(OH)D (nmol/l) |
|
|
|
|
|
| Overall |
55 |
44.3 (23.6) |
78.4 (24.5) |
34.1 (13.1) |
<0.001 |
| Fish oil capsules |
27 |
48.5 (24.8) |
80.4 (25.0) |
31.9 (15.3) |
<0.001 |
| Multivitamin tablets |
28 |
40.3 (22.0) |
76.5 (24.3) |
36.2 (10.4) |
<0.001 |
| p value (1) |
|
0.20 |
0.56 |
0.22 |
|
|
s-iPTH (pmol/l) |
|
|
|
|
|
| Overall |
55 |
5.9 (2.6) |
4.7 (2.1) |
−1.2 (2.5) |
0.001 |
| Fish oil capsules |
27 |
5.7 (2.6) |
4.9 (2.5) |
−0.9 (2.8) |
0.13 |
| Multivitamin tablets |
28 |
6.0 (2.7) |
4.5 (1.6) |
−1.4 (2.2) |
0.002 |
| p value (1) |
|
0.77 |
0.52 |
0.40 |
|
|
s-1,25(OH)2D (pmol/l) |
|
|
|
|
|
| Overall |
53 |
121 (41) |
134 (38) |
13 (48) |
0.057 |
| Fish oil capsules |
27 |
128 (38) |
136 (34) |
8 (45) |
0.37 |
| Multivitamin tablets |
26 |
113 (43) |
131 (42) |
18 (50) |
0.09 |
| p value (1) |
|
0.20 |
0.64 |
0.46 |
|
|
s-TRACP (U/l) |
|
|
|
|
|
| Overall |
54 |
2.65 (0.70) |
3.03 (0.69) |
0.38 (0.33) |
<0.001 |
| Fish oil capsules |
27 |
2.59 (0.80) |
3.01 (0.77) |
0.43 (0.31) |
<0.001 |
| Multivitamin tablets |
27 |
2.71 (0.61) |
3.04 (0.60) |
0.34 (0.36) |
<0.001 |
| p value (1) | 0.53 | 0.87 | 0.32 |
(1) Differences between types of supplement are tested using t test.
(2) Paired-samples t test for comparison of individual pre- and post-intervention concentration.