Table 3.
Predictors of change in biochemical parameters during four weeks of vitamin D3 supplementation (n = 55)
| Dependent variable |
Δs-25(OH)D (nmol/l) |
Δs-iPTH (pmol/l) |
Δs-1,25(OH)2D (pmol/l) |
Δs-TRACP (U/L) |
||||
|---|---|---|---|---|---|---|---|---|
|
B (95% CI) |
p value |
B (95% CI) |
p value |
B (95% CI) |
p value |
B (95% CI) |
p value | |
| Type of supplement (solid multivitamin tablet vs. gelatine fish oil capsule with n-3 fatty acids) (1) |
3.5 (2) (−3.6, 10.6) |
0.33 |
−0.4 (−1.5, 0.6) |
0.39 |
−1 (−22, 19) |
0.89 |
−0.08 (−0.25, 0.10) |
0.40 |
| Age, per 10 years |
1.4 (−3.2, 6.0) |
0.54 |
−0.5 (−1.3, 0.4) |
0.31 |
−10 (−27, 7) |
0.24 |
0.07 (−0.05, 0.19) |
0.25 |
| Gender, men vs. women |
1.0 (−6.4, 8.5) |
0.78 |
−1.3 (−2.5, 0.3) |
0.11 |
18 (−8, 46) |
0.17 |
0.04 (−0.16, 0.23) |
0.71 |
| Body mass index, per 5 kg/m2 |
−1.0 (−5.7, 3.7) |
0.68 |
−0.3 (−1.2, 0.6) |
0.48 |
−9 (−26, 8) |
0.30 |
0.05 (−0.07, 0.17) |
0.41 |
| Ethnic background, Tamil vs. Norwegian |
2.7 (−6.0, 11.3) |
0.54 |
−0.5 (−2.2, 1.2) |
0.54 |
−18 (−51, −14) |
0.26 |
0.27 (0.05, 0.49) |
0.016 |
| Baseline s-25(OH)D, per 10 nmol/l |
−1.1 (−2.6, 0.4) |
0.13 |
0.2 (−0.1, 0.5) |
0.10 |
−3 (−8, 3) |
0.31 |
−0.03 (−0.07, 0.01) |
0.10 |
| Baseline s-iPTH, per 5 pmol/l |
4.4 (−2.3, 11.2) |
0.20 |
−3.2 (−4.2, −2.3) |
< 0.001 |
−13 (−38, 12) |
0.30 |
−0.04 (−0.22, 0.14) |
0.66 |
| Baseline s-1,25(OH)2D, per 10 pmol/l |
−0.3 (−1.2, 0.6) |
0.51 |
0.0 (−0.2, 0.1) |
0.71 |
−8 (−10, −5) |
< 0.001 |
< −0.01 (−0.03, 0.02) |
0.81 |
| Baseline s-TRACP, per U/l | −4.7 (−9.8, 0.3) | 0.07 | 0.1 (−0.9, 1.1) | 0.86 | 9 (−10, 28) | 0.34 | −0.13 (−0.26, -0.01) | 0.039 |
1 Groups are randomised with regard to type of supplement. The analysis of type of supplement is adjusted for baseline serum concentration of the respective dependent variables, while the other analyses in the table are unadjusted.
2 Result previously published in: Holvik K et al., Br J Nutr 2007; 98: 620–5.