Table 2. Protection level induces by BALB/c mice immunization with rSjGALE plus Freund’s adjuvant and infected with 30 cercariae.
Groups | Adult worms | Liver eggs | Liver eggs/Female adult worm |
Mean±SD | Mean±SD | (% reduction) | |
(% reduction) | (% reduction) | ||
Trial 1 | |||
Control | |||
(PBS+CFA/IFA) | 8.8±3.8 | 28342±15972 | 9447±5324 |
n = 10 | |||
SjGALE | 5.6±2.9 | 13324±12379 | 3188±4536 |
n = 10 | (35.7%* ) | (53%**) | (66.2%**) |
Trial 2 | |||
Control | |||
(PBS+CFA/IFA) | 18.7±5.6 | 9911±6576 | 2265±1893 |
n = 10 | |||
SjGALE | 12.5±5.5 | 5312±2565 | 916±368 |
n = 8 | (33.0%*) | (46.4%**) | (59.5%**) |
Statistically significant compared to the control group (p<0.05),
(p<0.01).