Table 2. Dynamic parameters.
| Genes | Parameter | LIVER | BRAIN | ||
| IFNGFPa | IFNGFPApoa | IFNGFPa | IFNGFPApoa | ||
| ISG15 | kS_ISG (gene expression*h−1)b | 491 (7.31) | 2.05×10−3(21.12) | 6.08×10−4(17.11) | |
| kD_ISG (h−1) | 491 (7.31) | 0.127 (24.33) | |||
| IFN50_ISG15 (pg*mL−1) | 151 (0.47) | NA | NA | ||
| OAS | kS_OAS (gene expression*h−1) b | 0.0366 (81.69) | 7.37×10−5 (23.47) | 2.45×10−5 (23.47) | |
| kD_OAS(h−1) | 1.18 (87.29) | 0.101 (23.76) | |||
| IFN50_OAS (pg*mL−1) | 255 (43.14) | NA | NA | ||
a
Parameter estimates are listed together with the corresponding coefficient of variation [CV(%)] calculated as the ratio between the standard error and the estimate of the parameter.
b
Brain parameter units in gene expression*mL*pg−1*h−1.