Figure 2. XMRV knock down reduces tumorigenicity of 22Rv1 in vivo.

SCID mice (n = 6) were s.c. injected with 22Rv1 shLTR1+2, shLTR3 or with 22Rv1 control cells. For each cell line the final tumor amount was n = 12. 36d p.i. mice were sacrificed and tumors were analyzed for weight (A) and necrosis (B).