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. 2012 Jul 27;7(7):e42069. doi: 10.1371/journal.pone.0042069

Figure 4. Structure and site of mutation in the PmCesA3 gene associated with carboxylic acid amide (CAA) fungicide resistance.

Figure 4

(A) Intron/exon structure of the PmCesA3 gene. Numbers represent the size in base pairs. Point mutations in CAA-resistant mutants and the predicted amino acid substitution in the mutant gene products are indicated. (B) Alignment of partial amino acid sequences of CesA3 in P. melonis (PmCesA3), P. infestans (PiCesA3), and P. viticola (PvCesA3). TJ-90, TX-21, and TX-33 were wild-type isolates. D63-1 and D70-3 were dimethomorph-resistant mutants. F58-4 and F63-11 were flumorph-resistant mutants. I63-2 and I70-5 were iprovalicarb-resistant mutants. Mutations in CAA-resistant mutants of P. infestans, P. viticola and P. melonis are indicated by asterisks.