Table 1. Single nucleotide polymorphisms unique to strains in the 2006/2008 clade.
STM_MAL | STM | Description | LT2 | D23580+19 other strains | 2006/2008 strains | Amino acid | gene |
4573 | 179 | xylanase/chitin deacetylase | G | G | A | Trp→stop | yadE |
39 | 285 | inner membrane protein | G | G | A | Ala→Thr | - |
624 | 762 | fumarate hydratase | G | G | T | Leu→Ile | - |
756 | 935 | pyruvate dehydrogenase | C | T | C | His→Arg | poxB |
1383 | 1578 | nitrate reductase 2 beta subunit | C | C | T | Arg→Cys | narY |
1403 | 1598 | regulatory protein | G | A | G | No change | - |
2016 | 2150 | outer membrane protein | A | A | T | Asn→Lys | yehB |
2136 | 2277 | ribonucleotide-diphosphate reductase subunit alpha | T | T | C | Val→Ala | nrdA |
2170 | 2312 | hypothetical protein | C | T | C | Ile→Val | - |
intergenic space or other non-protein-coding region | G | A | G | - | - | ||
intergenic space or other non-protein-coding region | T | T | A | - | - | ||
2847 | 3046 | hemolysin | T | T | C | No change | yqfA |
2865 | 3066 | arginine exporter protein | C | T | C | Glu→Gly | yggA |
intergenic space or other non-protein-coding region | A | A | G | - | - | ||
3337 | 3509 | carboxylesterase BioH | A | A | C | Trp→Gly | bioH |
3719 | 3899 | ATP-dependent protease | G | G | A | Val→Ala | yifB |
4596 | 202 | glutamate-1-semialdehyde aminotransferase | T | T | C | Asn→Ser | hemI |
Single nucleotide polymorphisms relative to S. Typhimurium strains LT2 and D23580, distinguishing the seven strains of the 2006/2008 lineage from the large cluster of MDR strains (19) and the corresponding amino acid changes. STM and STM_Mal are systematic identification for coding sequences in LT2 and D23580.
Trp – tryptophan, Gln – glutamine, Arg – arginine, Ala – alanine, Thr – threonine, Leu – leucine, Ile – isoleucine, His – histidine, Cys – cysteine, Asn – asparagine, Gly – glycine.