Skip to main content
. 2012 Jul 27;7(7):e42357. doi: 10.1371/journal.pone.0042357

Figure 3. Correlation between PARP activity and aging in (A) Males (B) Females.

Figure 3

(A) PARP activity increases with age in male subjects. PARP activity increases significantly in male subjects aged between 0–77 years (line a; p<0.0001; n = 27). The data including the post-pubescent subjects (males only) shows no significant change in PARP activity with age (line b; p = 0.0913; n = 19). Pearson's correlation coefficient was a normally distributed population was r = 0.768 and r = 0.399 for line a, and line b respectively. An exponential (first-order) least squares fit was used to generate the nonlinear trend lines (line a and b). (B) PARP activity with age in female subjects (n = 27). The apparent increase in PARP activity with age (36–76 years) is not statistically significant in post-pubescent female subjects (p = 0.4390; n = 22). Spearman's Correlation coefficient for a non-normally distributed population was r = 0.174. An exponential (first-order) least squares fit was used to generate the nonlinear trend line.