Table 1. Differences between discrete categorised variable of the entire sample population.

Characteristic/Test	Newborns (0–1 years)	Young Adults (30–50 years)	Middle Age (51–70 years)	Elderly (>71 years)
Number in age groups (M/F)	8 (8/0)	12 (4/8)	23 (12/11)	5 (2/3)
Average Age mean yrs ± SEM	0.072±0.00	41.17±1.88	63.17±1.31	74.4±1.08
TBARS (mM MDA/mg protein), mean ± SEM	1.56±0.19	1.72±0.37	2.46±0.32	4.21±1.36* , **
pH2AX (FU/mg protein), mean ± SEM	12.83±2.24	21.70±4.69	46.05±1.30	123.40±1.08* , ** , ***
PARP Activity (ng NAD+ used/hr/mg protein), mean ± SEM	2.52±0.44	17.73±2.51*	20.69±1.63*	19.52±3.94*
NAD+ (ng NAD+/mg protein), mean ± SEM	8.54±1.55	2.74±0.41*	1.08±0.15*	1.06±0.19*
SIRT1 Activity (FU/mg protein), mean ± SEM	27.13±0.74	30.41±3.12	24.65±4.38	11.83±11.33

Data presented as mean ± SEM.

^*p<0.05 compared to newborns,

^**p<0.05 compared to young adults (30–50 years),

^***p<0.05 compared to middle age (51–70 years).