Table 3. HCV-1a NS3 UDPS mutation analysis.

	HCV-1a Amplicon NS3-I								HCV-1a Amplicon NS3-II
	V36				T54				R155				A156
ID	Baseline		Follow-up		Baseline		Follow-up		Baseline		Follow-up		Baseline		Follow-up
1	0	(13817)	0.05 M	(10541)	0	(13113)	0	(9386)	0	(2977)	0	(4854)	0	(2977)	0	(4853)
2	0.28 L; 0.04 A	(12481)	0	(5383)	0	(12305)	S 0.04	(5327)	0	(545)	0	(2780)	0	(545)	0	(2757)
3	0.03 A	(18294)	0	(15074)	0	(17191)	A 0.02	(13650)	0	(3534)	0	(2249)	0	(3532)	0	(2248)
8	0.08 L	(16263)	0	(4791)	0	(14215)	0	(4517)	0	(5453)	0	(8700)	0	(4456)	0	(8696)
10		NA		NA		NA		NA	0	(5379)	0.55 G	(8154)	0	(5379)	0	(8146)
11	0	(8687)	0	(6448)	0	(8687)	I 0.01	(10631)	0.14 S	(2873)	0	(2986)	0	(2873	0	(8116)
13	0	(20588)	0	(17458)	0	(19968)	0	(17201)	0	(5398)	0	(7147)	0	(5396)	0	(7144)
15	0	(18993)	4.53 M	(12836)	0	(18320)	S 0.35	(11769)	0	(5291)	0	(9032)	0	(5722)	0.01 T	(9032)

Percentage of UDPS reads with mutations. The parenthetical values indicate the number of reads analyzed. The bold numbers indicate variation present at a frequency above 0.1%. Underlined amino acids indicate resistant variants that were also observed by clonal sequencing at EOT.