Figure 3. LCModel-derived absolute metabolite levels in Institutional Units (IU) corrected for voxel CSF-content for subjects with ASD (red triangles) and healthy controls (green squares).

Horizontal bars denote group means. Values are shown for glutamate + glutamine (“Glx”; left) and creatine + phosphocreatine (right) in pACC. Note elevated Glx and deptressed Cr + PCr in subjects with ASD. *p<.05, **p<.01 (independent T-test following ANCOVA of rank-transformed, therefore non-parametric data.) Experiment 1.