Figure 5. The effects of oligomer, proto-fibril and fibril forms of insulin on neurite complexity in differentiated PC12 cells.

The criteria were quantified 12 h after treatment; A) primary neurites per cell; B) percent of bipolar cells and C) the ratio of nodes to primary neurites. * Significantly different from control cells. Statistical significances were achieved when p<0.05 (*p<0.05 and **p<0.01).