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. 2012 Jul 27;7(7):e40449. doi: 10.1371/journal.pone.0040449

Figure 4. Hierarchical clustering of microarray datasets.

Figure 4

Measurements of the 308 genes discriminating CCB- and CCB+ were extracted from different datasets: our study (A, B), GSE4260 (C), GSE18559 (D), GSE21005 (E) and GSE9526 (F). They were subjected to hierarchical clustering after log transformation and median centering of genes. The different types of sample are shown as coloured squares. The quality of the separation was measured by Fisher’s exact test on the main branch. CCGV, cumulus cells from immature oocyte at germinal vesicle stage; CCMII, cumulus cells from mature oocyte; CCB+, cumulus cells from mature oocyte yielding a blastocyst at day 5/6 of in vitro culture once fertilised; CCB-, cumulus cells from mature oocyte which stopped developing at the embryo stage at day 5/6 of in vitro culture once fertilised.