Table 5. Upregulated functions in CC_B+ compared to CC_B-.

Function	p-value
cytosolic large ribosomal subunit (sensu Eukaryota)	0.0006
zinc ion binding	0.0015
cation binding	0.0019
negative regulation of cell differentiation	0.0030
fatty acid biosynthesis	0.0040
negative regulation of myeloid cell differentiation	0.0045
cytosolic ribosome (sensu Eukaryota)	0.0048
organic acid biosynthesis	0.0060
carboxylic acid biosynthesis	0.0060
ribosome biogenesis and assembly	0.0063
large ribosomal subunit	0.0064
ion binding	0.0069
metal ion binding	0.0069
mesonephros development	0.0073
phosphocreatine metabolism	0.0073
porphobilinogen synthase activity	0.0073
10-formyltetrahydrofolate biosynthesis	0.0073
creatine kinase activity	0.0073
depyrimidination	0.0073
depurination	0.0073
male germ-line stem cell division	0.0073
transcription factor binding	0.0093
transcription regulator activity	0.0099

CC_B+, cumulus cells from mature oocyte yielding a blastocyst at day 5/6 of in vitro culture once fertilised;

CC_B-, cumulus cells from mature oocyte which stopped developing at the embryo stage at day 5/6 of in vitro culture once fertilised.