Figure 1. The profile of gene coverage.

The distribution of coverage of 18,594 gene coding regions of human CCDS by theoretical target region, target orthologous region and sequencing data from 3 species is shown. The sequencing coverage of each gene was inferred from one individual in each species. Sequencing data showed that 80.40%–80.45% of genes were covered ≥90% for both humans and chimpanzees, and 77.76% for macaques. Coverage of macaque CCDSs was higher than target orthologous region. The coverage of human and chimpanzee genes was close when concerns target region, and higher for macaque compared to target orthologous region.