Table 2.

mRNA splicing genes altered in expression in B6 in response to ethanol

Gene Symbol1	Gene Name	Fold Change (Etoh/Cont)
Ddx5	DEAD-box polypeptide 5 [helicase]	0.74
Hnrnpa2b1	Heterogeneous nuclear ribonucleoprotein A2/B1	0.64
Ncbp2	Nuclear cap binding protein subunit 2	0.75
Pabpc1	Poly (A) binding protein, cytoplasmic 1	0.71
Pnn	Pinin [splicing regulator]	0.65
Ppp4r2	Protein phosphatase 4, regulatory subunit 2	0.76
Prpf38a	PRP38 pre-mRNA processing factor 38 (yeast) domain containing A	0.72
Prpf38b	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	0.63
Prpf4b	PRP4 pre-mRNA processing factor 4 homolog B (yeast)	0.69
Rbm5	RNA binding motif protein 5	0.78
Rbm39	RNA binding motif protein 39	0.76
Sfpq	Splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	0.77
Sfrs18	Serine/arginine-rich splicing factor 18	0.66
Sfswap	splicing factor, suppressor of white-apricot homolog (Drosophila)	0.81
Srek1	Splicing regulatory glutamine/lysine-rich protein 1	0.64
Srsf1	Serine/arginine-rich splicing factor 1	0.72
Srsf6	Serine/arginine-rich splicing factor 6	0.64
Srsf7	Serine/arginine-rich splicing factor 7	0.67
Srsf10	Serine/arginine-rich splicing factor 10	0.62
Srsf11	Serine/arginine-rich splicing factor 11	0.78
Syncrip	Synaptotagmin binding, cytoplasmic RNA interacting protein	0.76
Tardbp	TAR DNA binding protein	0.66
Thoc6	THO complex 6 homolog (Drosophila) [mRNA transport to cytoplasm]	0.77

¹Mouse Genome Informatics database (http://www.informatics.jax.org).

²Fold change < 1 indicates reduced expression in response to ethanol relative to a value of 1. Mean = 0.68, SD = 0.16