FIG. 5.

PTU increases uptake of ¹²⁵I in FRTL-5 cells. FRTL-5 cells were maintained in a medium without TSH for 7 days and treated with 5 mM PTU or 1 mU/mL TSH with perchlorate (B) or not (A) for the indicated periods. I⁻ uptake was measured and expressed as counts per minute, which were normalized to DNA content. Representative results from three independent experiments are shown as the mean±SD of triplicate assays. *p<0.001, **p<0.0001.