Table 1.
Structural differences associated with migraine reported in previous imaging studies
| Patients | Controls | |||||
|---|---|---|---|---|---|---|
| (M/F) | (M/F) | Method | Results | Patients versus controls | Sex difference | Reference |
| 28 (2/26) | 28 (2/26) | 2 T VBM | no sign diff | no sign diff | NR | Matharu et al. (2003) |
| 35 (3/32) | 31 (0/31) | 1.5 T VBM | < | ACC, Ins, PCC | NR | Schmidt-Wilcke et al. (2008) |
| 24 (0/24) | 24 (0/24) | 3 T VBM | < | IPL, MFG | - | Schmitz et al. (2008) |
| 27 (6/21) | 27 (7/20) | 1 T VBM | < | IFG, ParOper, PCG, STG, TTG | NR | Valfre et al. (2008) |
| 20 (3/17) | 33 (4/29) | 1.5 T VBM | < | ACC, IFG, Ins, IPG, LG, MFG, | NR | Kim et al. (2008) |
| PCC, PCG, SFG, SPG | ||||||
| 16 (1/15) | 15 (2/13) | 3 T VBM | < | ACC, IFG, ITG, MFG, MTG, PCG, | NR | Rocca et al. (2006) |
| SFG, STG, Unc | ||||||
| > | PAG, Pons | |||||
| 28 (0/28) | 28 (0/28) | 3 T VBM | < | IPL SFG | – | Schmitz et al. (2008) |
| 24 (8/16) | 12 (3/9) | 3 T Cor. Th | > | SSC, V3A, MT | NR | DaSilva et al. (2007) |
| Total | ||||||
| (23/179) | (18/180) | |||||
VBM = voxel based morphometry; Cor. Th = cortical thickness; ACC = anterior cingulate cortex; IFG = inferior frontal gyrus; Ins = insula; IPG = inferior parietal gyrus; IPL = inferior parietal lobule; ITG = inferior temporal gyrus; LG = lingual gyrus; MFG = middle frontal gyrus; MT = middle temporal visual area; NR = ; PAG = periaqueductal grey; ParOper = parietal operculum; PCC = posterior cingulate cortex; PCG = precentral gyrus; SFG = superior frontal gyrus; SPG = superior parietal gyrus; SSC = somatosensory cortex; STG = superior temporal gyrus; TTG = transverse temporal gyrus; Unc = uncus; V3A = visual area 3a.