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. 2012 Jun 7;12:128. doi: 10.1186/1471-2334-12-128

Table 2.

Sensitivity, Specificity, Positive and Negative predictive values of Total lymphocyte count cut-off for various CD4 groups

  TLC cut-off (cells/mm3) Sensitivity (%) 95% CI Specificity (%) 95% CI PPV (%) NPV (%)
 
 1000
 72.22
 46.52 to 90.31
 94.44
 72.71 to 99.86
 100
 91.7
CD4 count <200
 1200
 72.22
 46.52 to 90.31
 100
 81.47 to 100.0
 100
 95.7
(cells/mm3)
 1400
 66.67
 40.99 to 86.66
 100
 81.47 to 100.0
 77.8
 94.1
 
 1600
 55.56
 30.76 to 78.47
 100
 81.47 to 100.0
 65.6
 91.7
 
 1000
 100
 88.4 to 100
 66.67
 9.4 to 99.2
 96.8
 100
CD4 count 200–499
 1200
 100
 88.4 to 101
 67.67
 9.4 to 99.3
 96.7
 66.7
(cells/mm3)
 1500
 96.67
 82.8 to 99.9
 100
 29.2 to 100
 100
 75.0
 
 1600
 93.33
 77.9 to 99.2
 100
 29.2 to 101
 100
 60.0
 
 1700
 95.45
 77.2 to 99.9
 63.64
 30.8 to 89.1
 84.0
 87.5
CD4 count ≥500
 1750
 96.45
 77.2 to 99.10
 72.73
 39.0 to 94.0
 87.5
 88.9
(cells/mm3)
 1800
 97.45
 77.2 to 99.11
 90.91
 58.7 to 99.8
 95.5
 90.9
  1900 98.45 77.2 to 99.12 100 71.5 to 100 100 91.7

TLC-Total lymphocyte count; PPV-Predictive positive value; NPV-Negative predictive value; 95% CI- 95% Confidence interval.