Figure 4.

Cytotoxic effects measured by LDH enzymatic activity in human skin cancer and normal human skin cells after treatment with RRM-MV or RRM-C. LDH levels were measured following treatment with 400 ng/mL of RRM-MV or RRM-C for 3 h. RRM-MV produced high cellular LDH levels in cancer cells. Results are average of three independent experiments. Cytotoxicity values were analysed using one-way ANOVA and Tukey post hoc test. They showed a significant difference between RRM-MV-treated cells and untreated cells (p < 0.01). Significant values are indicated with an *.