TABLE 3.
Subject no. | LC | CA (mmol/L blood) | (L blood/min/L liver tissue) | (mmol/min/L liver tissue) |
---|---|---|---|---|
1 | 0.13 ± 0.02 | 10.1 ± 2.1 | 0.014 ± 0.002 | 1.10 ± 0.48 |
2 | 0.14 ± 0.01 | 6.5 ± 1.3 | 0.029 ± 0.002 | 1.85 ± 0.60 |
3 | 0.12 ± 0.02 | 11.7 ± 1.6 | 0.011 ± 0.002 | 1.16 ± 0.40 |
4 | ND | 7.1 ± 0.5 | 0.019 ± 0.002 | ND |
5 | 0.17 ± 0.03 | ND | ND | ND |
6 | 0.14 ± 0.02 | 10.1 ± 0.6 | 0.020 ± 0.002 | 1.51 ± 0.53 |
7 | 0.10 ± 0.03 | 7.2 ± 0.6 | 0.025 ± 0.006 | 2.02 ± 1.10 |
8 | 0.11 ± 0.03 | 9.2 ± 0.7 | 0.024 ± 0.001 | 2.11 ± 0.96 |
Mean ± SE | 0.13 ± 0.01 | 8.3 ± 0.3 | 0.019 ± 0.001 | 1.41 ± 0.24 |
LC = lumped constant for 18F-FDGal; CA = mean arterial blood concentration of galactose during the 18F-FDGal PET study with galactose infusion; = systemic hepatic clearance of 18F-FDGal calculated from the PET study with galactose infusion; = maximum hepatic removal rate of galactose calculated from 18F-FDGal PET data with galactose infusion (Eq. 5); ND = not determined (in subject 4, no liver vein blood samples were obtained during PET study; in subject 5, the PET study with galactose infusion was not performed; mean ± SE, weighted mean ± SE of weighted mean.
Individual values are given as estimate ± SE of estimate.