Figure 7.
Distribution of drug targets and drug targets with virus interacting partners in pathways. Approximately half of the drug targets in the pathways appear to be targeted by viruses. However, some pathways have significant higher number of drug targets compared with drug targets with reported virus interactions namely, Pathway ‘A’ Canonical NF-kappaB pathway, Pathway ‘B’ HIF-1-alpha transcription factor network, Pathway ‘C’ Vif-mediated degradation of APOBEC3G, Pathway ‘D’ Electron Transport Chain and Pathway ‘E’ Signalling mediated by p38-alpha and p38-beta