Table 2.
Taxon grouping and summary of data. The table details the grouping of different strains of viruses and lists statistics on their interactions and the pathways they are linked to. Column 1: Taxon. The abbreviation indicated in brackets is used throughout the text. Column 2: Strains grouped together as the taxon indicated in column 1. For abbreviation comma or parenthesis is used; i.e., “Bacteriophage PBS2, lamda” reads “Bacteriophage lambda” and “Bacteriophage PBS2”, whereas Vaccinia virus (Copenhagen) indicates Vaccinia virus and Vaccinia virus Copenhagen. Column 3: Number of interactions in VirusMINT with human proteins for each strain in the grouped taxons. Column 4: Total number of interactions for the taxon group and the number of human proteins involved in the interactions, given in brackets. Column 5: Number of pathways each virus taxon group is linked to by way of PPI. Column 6: Percentage of the human proteins present in pathways that are targeted by the virus in at least one pathway
| Taxon | Grouped taxons | Virus PPI |
Total PPI |
Pathways | % proteins |
|---|---|---|---|---|---|
| Autographa californica nuclear polyhedrosis virus (AcMNPV) | Autographa californica nuclear polyhedrosis virus | 1 | 1(1) | 14 | 100 |
| Avian sarcoma virus (ASV) | Avian sarcoma virus strain PR2257 | 2 | 2(1) | 18 | 50 |
| Bacteriophage (PBS2) | Bacteriophage PBS2, lambda | 1, 1 | 2(1) | 1 | 50 |
| Bovine papillomavirus (BPV) | Bovine papillomavirus type 1, 2 | 28, 1 | 29(1) | 68 | 59 |
| Cercopithecine herpesvirus (CeHV) | Cercopithecine herpesvirus 12 | 4 | 4(1) | 14 | 75 |
| Cottontail rabbit papillomavirus (CRPV) | Cottontail rabbit papillomavirus, Kansas | 2, 3 | 5(4) | 0 | 0 |
| Ebola virus (EBOV) | Ebola virus strain Zaire Mayinga | 1 | 1(1) | 2 | 100 |
| Epstein–Barr virus (EBV) | Epstein-Barr virus strain GD1, B95–8 | 121, 24 | 145(13) | 121 | 57 |
| Fowl adenovirus (FAdV) | Fowl adenovirus 1 strain CELO/Phelps | 2 | 2(1) | 10 | 50 |
| Hepatitis B virus (HBV) | Hepatitis B virus | 8 | 8(3) | 10 | 50 |
| Hepatitis C virus (HCV) | Hepatitis C virus genotype 1a isolate 1, 1b isolate BK, 1a isolate H, 1b isolate Taiwan, 1b isolate Con1, subtype 1a and 1b | 22, 4, 1, 4, 1, 3, 2, 1 | 38(12) | 101 | 59 |
| Hepatitis E virus (HEV) | Hepatitis E virus strain Burma, Mexico | 2, 1 | 3(2) | 0 | 0 |
| Hepatitis delta virus (HDV) | Hepatitis delta virus isolate American, D380 | 1, 1 | 2(2) | 3 | 100 |
| Human SARS coronavirus (SARS-CoV) | Human SARS coronavirus | 3 | 3(2) | 6 | 67 |
| Human T-cell leukaemia virus (HTCLV) | Human T-cell leukaemia virus type I isolate Caribbean | 2 | 2(1) | 1 | 50 |
| Human T-lymphotropic virus (HTLV) | Human T-lymphotropic virus 1 | 3 | 3(3) | 8 | 33 |
| Human adenovirus (HAdV) | Human adenovirus 2, 7, 9, 31, E, 12, 5, B serotype 3 | 19, 1, 1, 1, 2, 16, 53, 4 | 97(25) | 106 | 70 |
| Human cytomegalovirus (HHV-5) | Human cytomegalovirus, AD169, Towne | 1, 1, 1 | 3(3) | 12 | 100 |
| Human herpesvirus (HHV) | Human herpesvirus 1(17, Patton), 2, 3, 6, 8 | 4(61, 1), 1, 1, 1, 4 | 73(16) | 139 | 63 |
| Human immunodeficiency virus (HIV) | Human immunodeficiency virus type 1 (12, ARV2/SF2, ELI, NDK, HXB3, Lai), 2 isolate BEN | 583(19, 4, 3, 1, 2, 4), 1 | 617(33) | 289 | 48 |
| Human papillomavirus (HPV) | Human papillomavirus type 8, 11, 1a, 31, 45, 58, 6b, 3, 16, 18 | 8, 39, 8, 10, 1, 1, 16, 2, 115, 43 | 243(37) | 153 | 56 |
| Influenza A virus (FLUAV) | Influenza A virus strain A/Turkey/Oregon/71 H7N3, A/Puerto Rico/8/34 H1N1, A/Aichi/2/1968 H3N2 | 1, 10, 1 | 12(7) | 57 | 90 |
| JC polyomavirus (JCPyV) | JC polyomavirus | 2 | 2(1) | 3 | 50 |
| Murine adenovirus (MAV) | Murine adenovirus 1 | 1 | 1(1) | 4 | 100 |
| Murine polyomavirus (MPyV) | Murine polyomavirus strain 3 | 4 | 4(3) | 16 | 100 |
| Poliovirus (PV) | Poliovirus type 1 strain Sabin | 2 | 2(1) | 11 | 100 |
| Rous sarcoma virus (RSV) | Rous sarcoma virus strain Prague C, Schmidt-Ruppin A, Schmidt-Ruppin D | 1, 1, 3 | 5(3) | 3 | 60 |
| Saimiriine herpesvirus (SaHV) | Saimiriine herpesvirus 2 strain 11, 488 | 1, 2 | 3(2) | 49 | 100 |
| Sendai virus (SeV) | Sendai virus strain Fushimi | 1 | 1(1) | 0 | 0 |
| Simian virus (SV) | Simian virus 40, 5 strain W3 | 45, 2 | 47(5) | 121 | 79 |
| Vaccinia virus (VACV/VV) | Vaccinia virus (Copenhagen, Western Reserve/WR, L-IVP) | 3(6, 15, 7) | 31(12) | 62 | 70 |