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. 2012 May 31;9:115. doi: 10.1186/1742-2094-9-115

Table 2.

Microglia properties by cell line

  Primary Microglia BV2 N9 HMO6 EOC HAPI
MAC-1
 +
 +
 +
 +
 +
 +
LPS stimulation
 +
 +
 +
 +
 +
 +
lL-1β release
 +
 -
 +
 -
 N/A
 +
TNF- release (Following LPS)
 +
 +
 +
 +
 N/A
 +
Phagocytosis
 +
 +
 +
 +
 +
 +
Peroxidase
 -
 -
 -
 -
 -
 -
Non-specific esterase
 +
 +
 +
 +
 +
 +
GFAP
 -
 -
 -
 -
 -
 -
GC
 -
 -
 -
 -
 -
 -
·NO production
 +
 +
 +
 -
 +
 +
Aβ induced lL-β
 +
 +
 +
 -
 N/A
 N/A
Aβ induced TNF-
 +
 +
 +
 +
 N/A
 N/A
Aβ phagocytosis
 +
 +
 +
 N/A
 N/A
 N/A
Number of articles in Pub Meda 302 142 91 8 18 19

The table represents properties of individual cell lines as reported by citations in the PubMed Database (http://www.ncbi.nlm.nih.gov/). (+) Positive for trait, (−) negative for trait. aSpecific PubMed search term ‘primary microglial cell culture’ (from year 2000 to present; includes both studies of endogenous microglia as well as primary cultures of microglial isolates). Aβ, amyloid β; GC, galactocerebroside; GFAP, glial fibrillary acidic protein; LPS, lipopolysaccharide.