Table 3.
Genotype distribution and allelic frequencies ofNFKB1rs4648068 polymorphism in gastric cancer patients and control subjects
| Gastric Cancer | Controls | AOR (95%CI)Δ | PvalueΔ | |
|---|---|---|---|---|
| Cases (n) |
248 |
192 |
/ |
/ |
| Age |
57 ± 11* |
53 ± 15 |
/ |
/ |
| Gender (M/F) |
160/88** |
119/73 |
/ |
/ |
| Genotype |
|
|
|
|
| GG(%) |
53(21.3)# |
20(10.4) |
1.92(1.02-3.60) |
0.042 |
| AG(%) |
117(47.2) |
115(59.9) |
0.75(0.48-1.16) |
0.195 |
| AA (%) |
78(31.5) |
57(29.7) |
1.00 |
|
| Allelic frequencies |
|
|
|
|
| G(%) |
223(45.0) |
155(40.4) |
1.13(0.99-1.36) |
0.198 |
| A(%) | 273(55.0) | 229(59.6) | 1.00 |
* and **, P > 0.05 and minor allele frequency (MAF) = 0.346; M, male; F, female; #, P = 0.042 (GG is risk factor); Δ, multivariate logistic regression adjusted by age and gender.