Figure 3.

CPA produced by the κ-opioid receptor agonist U69,593 in control and CCK-8 infusion rats. For the CPA score the amount of time spent in the conditioning compartment on the post-conditioning days were subtracted from the amount of time spent in the same compartment on the pre-conditioning day. Compared with control rats, no significant differences of CPA scores were observed in the rats with post training CCK-8 infusion. Results were presented as means ± SE. Statistical significance was determined by Two-way Repeated measurement ANOVA followed by Bonferroni posttests, n=5 for each group.