Table 2.

Affinity profile (IC₅₀in nanomolar) of AT1S and AT2S for the human sst_1-5receptors

Code	hsst1	hsst2	hsst3	hsst4	hsst5
SS14	1.9 ± 0.5 (5)	0.7 ± 0.2 (5)	3.3 ± 1.7 (4)	1.6 ± 0.8 (4)	4.2 ± 0.7 (3)
SS28	2.7 ± 0.5 (3)	2.5 ± 0.1 (3)	2.2 ± 0.6 (3)	2.1 ± 0.4 (3)	2.0 ± 0.2 (3)
AT1S	5.1 ± 1.4 (3)	2.8 ± 0.3 (3)	1.8 ± 0.6 (3)	2.5 ± 0.6 (3)	17 ± 3 (3)
AT2S	14 ± 2 (3)	1.5 ± 0.3 (3)	2.4 ± 0.5 (3)	3.7 ± 0.7 (3)	12 ± 2 (3)

Mean ± SEM (numbers in parentheses = number of experiments). The profile for the human sst_1-5 receptors was determined by receptor autoradiography experiments; [Leu⁸,DTrp²²,¹²⁵I-Tyr²⁵]SS28 was used as the radioligand and SS14 and SS28 as control compounds.