Table 2.
Cell Lines | |||||||
---|---|---|---|---|---|---|---|
DLD-1 | T-47D | HCT-116 | MCF-7 | MDA-MB-231 | K562 | Molt 4 | |
1 | 12.9 | 12.0 | 6.3 | 11.5 | 11.4 | 4.3 | 6.3 |
2 | – c | – c | – c | – c | – c | 13.7 | 17.8 |
Doxorubicin b | 0.42 | 0.28 | 0.89 | 2.2 | 1.3 | 0.14 | 0.009 |
a Compounds 3–5 was inactive against all seven cell lines (IC50 > 20 μg/mL); b Clinical anticancer drug used as a positive control; c NA, not active at 20 μg/mL.