Figure 5. OPC maturation into MBP+ OLs in OPC/DRG co-culture.
Passage 1 OPCs co-cultured with rat embryonic DRGs resulted in OPC maturation into highly arborized (A–C) O4+ and (D–F) O1+ OLs 7 days following plating. (G–I) Numerous OLs formed MBP+ processes around β-tubulin+ DRG axons. All photomicrographs are 10X magnification.