C57BL/6 Mice were fed alcohol (EtOH) for 6 weeks and were exposed to 12.5% HDE intranasally for 3 weeks (n = 5). (A) Total cells counted in BALF: Total cellularity collected in the bronchoalveolar lavage fluid (BALF) increased nearly 10-fold in the HDE and alcohol + HDE groups however there is no statistical difference between the HDE and co-exposure group. (B) Total cells counted in BALF per cell type: Inflammatory cells quantified from BALF detailed a statistical increase in neutrophils in the HDE group, which is followed by a reduction in neutrophils in the alcohol + HDE group. Inflammatory cells quantified from BALF detailed a difference in distribution between alcohol + HDE and the HDE group alone. (C) Percentage of each type of cells coutnted: Neutrophils increased from less than 1% in the control to 65% in the HDE group and back down to 37% in the alcohol + HDE group. (* p < 0.05 vs. control ANOVA, Bonferroni post-test) (M = macrophages, P = neutrophils, EO = eosinophils, L = lymphocytes).