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C57BL/6 Mice were fed alcohol (EtOH) for 6 weeks and were exposed to 12.5% HDE intranasally for 3 weeks (n = 5). Lung sections from H&E stained slides revealed upon histological evaluation that HDE exposed C57BL/6 mice exhibited the highest levels of peribronchial inflammation. The alcohol + HDE exposed group showed a marked reduction in HDE-induced mononuclear cellular aggregates.
