Table 2. Adjusted means of change in weight and WOMAC scores generated from mediation analyses, path β.
| Adjusted mean changea (s.e.) | P for difference | Raw mean change (s.d.) | Effect size for change between ILI and DSEb | |
|---|---|---|---|---|
| Weight (kg) changea | N = 1,755 | |||
| DSE | −0.78 (0.49) | 0.001 | −0.90 (5.14) | −1.18 |
| ILI | −9.02 (0.48) | −9.08 (8.31) | ||
| WOMAC pain changec | N = 1,758 | |||
| DSE (n = 856) | −0.11 (0.23) | 0.04 | −0.28 (3.57) | 0.06 |
| ILI (n = 902) | −0.41 (0.22) | −0.51 (3.45) | ||
| WOMAC physical function changec | N = 1,759 | |||
| DSE (n = 857) | −1.28 (0.69) | 0.001 | −0.73 (11.32) | −0.15 |
| ILI (n = 902) | −2.73 (0.67) | −2.30 (9.92) | ||
| WOMAC stiffness subscale changec | N = 1,759 | |||
| DSE (n = 857) | −0.34 (0.11) | 0.16 | −0.24 (1.72) | −0.07 |
| ILI (n = 902) | −0.44 (0.11) | −0.36 (1.69) | ||
| WOMAC Summary Score changec | N = 1,759 | |||
| DSE (n = 857) | −1.73 (0.96) | 0.004 | −1.22 (15.34) | −0.13 |
| ILI (n = 902) | −3.54 (0.94) | −3.10 (13.57) |
DSE, Diabetes Support and Education; ILI, Intensive Lifestyle Intervention; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index.
a
Adjusted for age, gender, race/ethnicity, study site, Beck Depression Inventory Score, use of nonsteroidal anti-inflammatory drugs and baseline weight.
b
Effect size calculated as (ILImean − DSEmean)/pooled standard deviation.
c
Adjusted for baseline values of outcome variable, age, gender, race/ethnicity, study site, Beck Depression Inventory Score, use of nonsteroidal anti-inflammatory drugs and baseline weight.