Table 2.
Temporal Trend of Knee Pain and Knee Osteoarthritis in NHANES and Framingham Osteoarthritis Study
| Males | Females | |||
|---|---|---|---|---|
| Time 2 vs. 1 PR (95% CI) |
Time 3 vs. 1 PR (95% CI) |
Time 2 vs. 1 PR (95% CI) |
Time 3 vs. 1 PR (95% CI) |
|
| NHANES Knee Pain (1971–1994*) | ||||
| Crude | 1.39 (1.01, 1.91) | 1.86 (1.30, 2.49) | 1.21 (0.95, 1.56) | 1.79 (1.40, 2.33) |
| Adjusted for Age | 1.40 (1.06, 1.92) | 1.85 (1.33, 2.54) | 1.21 (0.92, 1.57) | 1.79 (1.35, 2.35) |
| Adjusted for Age, BMI | 1.36 (1.03, 1.89) | 1.66 (1.22, 2.31) | 1.22 (0.95, 1.62) | 1.66 (1.29, 2.21) |
| NHANES Knee Pain (1999–2004†) | ||||
| Crude | 1.13 (0.78, 1.69) | 1.31 (0.96, 2.00) | 1.42 (1.03, 1.95) | 1.29 (0.96, 1.85) |
| Adjusted for Age | 1.14 (0.75, 1.65) | 1.32 (0.91, 1.65) | 1.42 (1.02, 1.96) | 1.30 (0.91, 1.77) |
| Adjusted for Age, BMI | 1.13 (0.80, 1.64) | 1.24 (0.89, 1.80) | 1.37 (1.00, 1.90) | 1.34 (0.97, 1.85) |
| FOA Study Knee Pain (1983–2005‡) | ||||
| Crude | 1.39 (0.87, 2.14) | 3.87 (2.70, 5.77) | 1.26 (0.96, 1.66) | 2.39 (1.87, 3.08) |
| Adjusted for Age | 1.49 (0.89, 2.42) | 3.89 (2.74, 5.78) | 1.22 (0.93, 1.60) | 2.38 (1.88, 3.04) |
| Adjusted for Age, BMI | 1.31 (0.79, 2.14) | 3.18 (2.14, 4.93) | 1.16 (0.90, 1.54) | 2.09 (1.60, 2.75) |
| FOA Study Knee Symptomatic OA (1983–2005‡) | ||||
| Crude | 1.33 (0.76, 2.53) | 3.52 (2.17, 5.76) | 1.31 (0.95, 1.95) | 2.04 (1.47, 2.97) |
| Adjusted for Age | 1.49 (0.80, 2.75) | 3.54 (2.24, 6.46) | 1.20 (0.85, 1.73) | 2.04 (1.46, 2.92) |
| Adjusted for Age, BMI | 1.36 (0.75, 2.52) | 2.81 (1.72, 5.00) | 1.13 (0.82, 1.62) | 1.60 (1.15 2.32) |
*
NHANES 1971–1994: Time 1=1974–1975, Time 2=1976–1980, Time 3=1988–1994 among Non-Hispanic White and Mexican American for people 60 to 74 years of age.
†
NHANES 1999–2004: Time 1=1999–2000, Time 2=2001–2002, Time 3=2003–2004 among Non-Hispanic White and Mexican American for people 60 to 74 years of age.
‡
Framingham OA Study 1983–2005: Time 1=1983–1985, Time 2=1992–1995, Time 3=2002–2005, using the query on knee pain in the past month over the previous 12 months for those 70 years or older.
Abbreviations: NHANES-National Health and Nutrition Examination Survey; FOA-Framingham Osteoarthritis Study; BMI-body mass index; PR-prevalence ratio