Figure 1. Inferred amino acid sequence showing the type and position of primary tumor mutations within exon 11 in (A) c-kit and exon 18 in (B) pdgfra compared to a consensus reference sequence (gi34099 and gi60391308, respectively, top sequence). Letters in the amino acid sequence for each clone indicate substitutions; insertions are shown by the addition of the appropriate amino acids in the insertion site; boxed asterisks indicate stop codons; gray boxes show amino acid deletions.