Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2012 Jul 30.

Published in final edited form as: Circ Res. 2010 Jul 29;107(7):913–922. doi: 10.1161/CIRCRESAHA.110.222703

Table 1.

Myocardial Infarct phenotype before and after treatment (values determined by cMRI)

Parameter	Groups	Baseline	Post-MI	Week 2 Post-Inj	Week 8 Post-Inj	p-value
Infarct Size (%LV mass)	CCM	0	24.4±3.2	23.5±1.7	26.3±1.5
Infarct Size (%LV mass)	MSCs	0	24.9±2.4	14.5±3.1	10.9±5.1	p=0.002^*^†
Infarct Volume (ml)	CCM	0	13.4±1.3	11.9±1.0	13.4±1.0	p=0.009^*
Infarct Volume (ml)	MSCs	0	11.7±1.7	7.7±1.8^†	7.3±3.5^†	p≤0.001^†
LV mass (g)	CCM	51.2±3.3	51.2±3.3	51.7±5.0	51.5±6.0
LV mass (g)	MSCs	45.9±3.6	45.9±3.6	51.2±4.2	62.1±5.4	p=NS
Circumferential Extent of MI (%LV)	CCM	0	41.5±5.0	44.8±2.4	38.04±4.3
Circumferential Extent of MI (%LV)	MSCs	0	38.8±4.0	27.8±6.5	27.6±12.1	p=NS
End-Diastolic Volume (ml)	CCM	33.2±3.4	38.8±4.0	43.0±4.8	40.5±1.2
End-Diastolic Volume (ml)	MSCs	32.2±2.4	34.2±3.8	41.0±4.7	46.5±10.7	p=NS
End-Systolic Volume (ml)	CCM	20.3±2.3	28.9±3.6	30.8±4.1	28.2±0.9
End-Systolic Volume (ml)	MSCs	20.1±1.6	24.5±2.6	26.7±5.1	31.4±11.3	p=NS
Stroke Volume (ml)	CCM	12.9±1.3	9.8±1.1	12.2±0.8	12.2±0.3	p= 0.003^†
Stroke Volume (ml)	MSCs	12.1±1.0	9.7±1.3	14.3±1.4^□	15.1±1.1^†	p=0.005^□
Heart Rate	CCM	86.2±6.8	82.2±3.0	69.1±1.5	81.1±19.5
Heart Rate	MSCs	102.5±9.0	85.7±4.3	81.0±5.5	84.1±17.3	p=NS
Ejection Fraction	CCM	39.1±1.6	25.8±3.1	29.1±1.4	30.2±0.4	p=0.042^□
Ejection Fraction	MSCs	37.8±1.6	27.9±1.1	37.0±5.0^□	36.4±9.4^†	p=0.026^†

^*

indicates p values significant between groups

^□

indicate p values significant within group

^†

indicate p values significant within group