The proportion of patient with donor-specific antibodies (DSAs) increases after an allograft nephrectomy. (A) Proportions of patients with DSAs, anti–human leukocyte antigen (anti-HLA) class I DSAs, and anti-HLA class II DSAs who did or did not have an allograft nephrectomy. (B) Kinetics of DSAs after an allograft nephrectomy. (C) Mean fluorescence intensity of de novo immunodominant anti-HLA class I DSAs. (D) Mean fluorescence intensity of de novo immunodominant anti-HLA class II DSAs. FU, follow-up; GL, graft loss; GN, graft nephrectomy.