Table 3.
Histologic analyses of allograft nephrectomies
| Patients with DSAs at Last Follow-Up (n=34) | Patients without DSAs at Last Follow-Up (n=8) | P Value | Patients with an Allograft Nephrectomy for Clinical Symptoms (n=17) | Patients with a Systematic Allograft Nephrectomy (n=17) | P Value | |
|---|---|---|---|---|---|---|
| t | 0 (0–3) | 0 (0–2) | 0.4 | 0 (0–3) | 0 (0–3) | 0.60 |
| i | 0 (0–3) | 0 (0–1) | 0.7 | 0 (0–3) | 0 (0–1) | 0.10 |
| g | 0 (0–3) | 0 (0–3) | 0.9 | 0 (0–3) | 0 (0–3) | 0.25 |
| v | 0 (0–3) | 0 (0–3) | 0.7 | 1 (0–3) | 0 (0–3) | 0.08 |
| ah | 3 (0–3) | 3 (3–3) | 0.1 | 3 (0–3) | 3 (2–3) | 0.06 |
| cg | 0 (0–3) | 0 (0–3) | 0.5 | 0 (0–3) | 0 (0–3) | 0.60 |
| ci | 3 (1–3) | 3 (0–3) | 0.5 | 1 (0–3) | 3 (0–3) | 0.20 |
| ct | 3 (1–3) | 3 (1–3) | 0.6 | 3 (1–3) | 3 (1–3) | 0.20 |
| cv | 3 (0–3) | 3 (0–3) | 0.4 | 3 (0–3) | 3 (0–3) | 0.90 |
| mm | 2 (0–3) | 1 (0–3) | 0.9 | 1 (0–3) | 2 (0–3) | 0.80 |
| ti | 3 (0–3) | 0 (0–2) | 0.002 | 2 (0–3) | 2 (0–3) | 0.95 |
| PTc | 0 (0–3) | 0 (0–3) | 0.8 | 0 (0–3) | 0 (0–3) | 0.74 |
| Positive C4d staining | 19 (55.9%) | 1 (12.5%) | 0.05 | 10 (59%) | 9 (53%) | 0.99 |
DSA, donor-specific antibodies; t, tubulitis; i, mononuclear cell interstitial inflammation; g, glomerulitis; v, intimal arteritis; ah, arteriolar hyaline thickening; cg, allograft glomerulopathy; ci, interstitial fibrosis; ct, tubular atrophy; cv, vascular fibrous intimal thickening; mm, mesangial matrix increase, ti, total interstitial inflammation; PTc, peritubular capillaritis.