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Domain organization of the EspA and EspC hybrid histidine kinases. Percent amino acid identity for the indicated domains is represented by shaded areas. The invariant histidine (H) residues in the dimerization and histidine phosphotransfer domains (DHp) and invariant aspartate (D) residues in the receiver (REC) domains are indicated. FHA, forkhead-associated domain; MASE1, predicted integral membrane sensory domain.
