Table 4.

Results of univariate and multivariate Cox proportional hazards models for demographic and clinical variables

Variable	Unadjusted HR	P	Adjusted HR	P
Age
0–19 years	0.05 (0.02–0.13)	<0.001	0.04 (0.01–0.12)	<0.001
20–39 years	0.09 (0.03–0.24)	<0.001	0.09 (0.03–0.27)	<0.001
40–59 years	0.16 (0.07–0.37)	<0.001	0.16 (0.06–0.40)	<0.001
60–79 years	0.35 (0.15–0.81)	0.014	0.46 (0.19–1.12)	0.088
80+ years	Reference		Reference
Sex
Male	Reference		Reference
Female	1.14 (0.73–1.77)	0.569	1.17 (0.74–1.86)	0.500
Race
White	Reference		Reference
Black	2.37 (1.44–3.91)	<0.001	1.84 (1.08–3.15)	0.026
Other	0.82 (0.35–1.91)	0.645	0.96 (0.41–2.27)	0.928
Tumor Size
<28 mm	Reference		Reference
≥28 mm	1.86 (1.06–3.25)	0.031	2.64 (1.47–4.75)	0.001
Unknown	1.11 (0.60–2.06)	0.743	1.13 (0.60–2.14)	0.710
Histology
Papillary	1.49 (0.73–3.04)	0.276	1.31 (0.61–2.81)	0.483
Adamantinomatous	1.13 (0.69–1.86)	0.619	1.39 (0.83–2.34)	0.207
Craniopharyngioma NOS	Reference		Reference
Surgical treatment
Observation or biopsy	Reference		Reference
Subtotal resection	0.39 (0.21–0.73)	0.003	0.45 (0.23–0.85)	0.014
Gross total resection	0.96 (0.58–1.59)	0.877	1.22 (0.71–2.08)	0.475
Unknown	1.01 (0.137–7.45)	0.991	2.06 (0.25–17.17)	0.505
Radiation treatment
No radiation	Reference		Reference
Radiation	0.50 (0.26–0.94)	0.032	0.45 (0.23–0.86)	0.016
Unknown	0.55 (0.08–3.99)	0.557	0.57 (0.08–4.28)	0.588

Abbreviations: NOS, not otherwise specified.